An article was published in the New England Journal of Medicine Dec 30, 2010 reporting 2 cases of deer- associated parapoxvirus in humans in 2008. Both cases were associated with hunting accidents with white-tailed deers, one in Virginia and one in Connecticut and were reported to the CDC within a week of each other. Both hunters cut a finger in the process of dressing the deers. The hunters in each case reported that the deers seemed to be healthy.
The wounds did not heal (as cuts normally would) but rather formed into inflamed, raised bumps. In each case, the lesion progressed into a nodule (approximately 1 cm) and medical attention was sought. The second man experienced a fever during this time but the first man did not report any other symptoms. The lesion remained localized
Lab testing confirmed the presence of parapoxvirus, which typically causes symptoms in deer, cattle, goats, and sheep (known as ruminants). In the US, parapoxvirus is only likely to affect people in close contact with the aforementioned animals, whether through direct contact or possibly through fomites. The diagnosis seems dependent on a physician's knowledge of contact with an animal and lab testing
Full article: http://www.nejm.org/doi/full/10.1056/NEJMoa1007407#t=articleTop