Every year we play a public health game with the influenza vaccine. We make a bet as to which strains of the virus will wreak havoc on us and put those into the annual flu vaccines that are distributed world-wide. And when we get it wrong, the results can be devastating.
Research being done at the University of Melbourne on the human body’s response to influenza virus infection is revealing exciting information that could help us develop a universal influenza vaccine. What they found is that certain T cells in our body - CD8+ T cells - are cross reactive across IAV, IBV, and ICV. This is remarkable because our current flu vaccines are hardly able to cross react with different substrains of influenza A, B, and C, much less across all three strains! The implications of this could mean that in the coming years researched will be able to develop a universal flu vaccine to protect against all strains including ICV which can cause severe disease in children. The researchers are planning ahead as they already have a patent on the discovery meaning they are the only ones who can develop the vaccine.
Renata Starbird
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