Researchers have been looking into the potentially deadly implications of “viral sex” or what is officially termed as viral re-assortment. This is the process by which viruses combine genomes and mix to form new strains with different mutations. Specific concerns of this come from researchers who have been monitoring bird influenza strains H7N9 and H5N8. Fortunately, re-assortment between the avian strains and the current human strain is limited by a few key factors. Primarily, “packaging signals” make it difficult for the RNA genome of the avian strains to combine with the human one. Secondly, Maria White (the head researcher on the project), claims that key sequence differences would also make recombination unlikely. However, White conducted subsequent studies in guinea pigs in which hemaglutinin (the receptor that allows influenza to bind to host cells) were able to mutate when both strains were present in order to produce a new type of flu virus. This potential for mutation is a daunting this to face because of a lack of knowledge about how to prepare for such an eventuality. While most people are not at risk of contracting a version of the avian flu, those who come into direct contact with birds frequently put themselves at risk of contracting it, meaning that a hybrid strain could come from a high exposure area such as a poultry farm.
-India Robinson
For more information visit https://www.sciencedaily.com/releases/2019/02/190212160015.htm
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