Thursday, March 21, 2019

Getting infected with the flu...for science? (Promising new flu vaccine)

A novel influenza vaccine being developed by FluGen, a subgroup of the Swiss biotech firm SGS, is showing remarkable promise in a Phase 2 clinical trial in humans. The vaccine aims to protect against Influenza A H3N2. This strain is important because its more severe than other strains and especially because it has an especially high mutation rate. This makes it one of the hardest influenza strains to consistently develop effective vaccines against. Last year’s H3N2 vaccine was only about 6% effective. Its important to note that last year’s flu vaccine overall was NOT only 6% effective. Since the vaccine is multi-valent, the vaccine can be effective overall even if it fails with one of the strains it was meant to protect against. The vaccine in question is interesting because though it is live attenuated, it is attenuated in a novel way: it has been molecularly engineered such that the virus can only complete one replication cycle after it has been administered (as a nasal spray). The craziest thing about this news to me though, is not the ingenuity of the researchers in their approach, but the design of the trial with which they’ve tested it. In a placebo controlled study with 99 participants. Half the participants received the vaccine, and the other half received a placebo. Then, all the participants were (willingly!) infected with H3N2 influenza virus. Essentially, they consented to a 50% chance of being given the flu with no prophylaxis. So far, it appears participants who received the vaccine did in fact have lower viral loads once infected. There’s still a lot to be done before this vaccine is even ready to be considered for market, but its an exciting step in the development of ever more efficacious flu vaccinations. 

~Lisa Manzanete

Reference:
  • https://www.healio.com/infectious-disease/influenza/news/online/%7B9bbd2f2d-6557-4c86-a7bd-ed13bc284285%7D/novel-flu-vaccine-shows-efficacy-against-mismatched-h3n2-virus
  • https://www.sgs.com/en/news/2019/03/successful-phase-2-clinical-trial-results-for-novel-influenza-vaccine 
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13 comments:

  1. [HOW I GOT CURED FROM GENITAL HERPES VIRUS )
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  2. I contracted hpv' i was told there is no hpv cure except treatment to control it, i totally lost of hope all i could think loosing my life because it was so embarrass for been hpv patient. some weeks ago i read possible natural cure which was guarantee And I ordered the treatment after one week i got 100% cure. I'm so excited to shear this testimony to every article for others living with hpv there is possible natural treatment to eliminate the virus email Dr Onokun, his herbal clinic address; Dronokunherbalcure@gmail.com

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  3. I contracted hpv' i was told there is no hpv cure except treatment to control it, i totally lost of hope all i could think loosing my life because it was so embarrass for been hpv patient. some weeks ago i read possible natural cure which was guarantee And I ordered the treatment after one week i got 100% cure. I'm so excited to shear this testimony to every article for others living with hpv there is possible natural treatment to eliminate the virus email Dr Onokun, his herbal clinic address; Dronokunherbalcure@gmail.com

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  4. I has suffered for Human papillomavirus HPV) for 2years, I was given some tablets at the hospital but I refused to take it, They said I have to be on it for life so I don't want take a drugs everyday for life. No point in taking medicine everyday when u won't get cure from it and I was advice to seek for natural herbal cure, after some time I found dr onokun is the most trustful herbalist that have herbs to cure wicked symptom's,I emailed dr onokun, for 2weeks been his patient he cured my (HPV) with his herbal. I only used his natural herbs for two weeks it was 100% cure. I'm not (HPV) patient anymore. I'm happy about it i finally got cured out of this mess been in my body for 2years. I also recommend you if you're living with (HPV) or herpes symptoms i also want you to be free contact dr onokun with the email attach to my post. Dronokunherbalcure@gmail.com

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  6. So surprise when i found that HSV 1&2 could be cured with Dr Ohunyom herbal remedy, this disease almost destroy my face, and my mouth with sores. i took many traditional medicine here in United state, but none could work. even visited my mother village in South africa still couldn't find a cure, but i was so surprise that after contacting Dr Ohunyom. And after done discussing with him i was cured with his herbal in 2 weeks. i confirmed his good work by my test result, do not delay to contact this true healer. Dr Ohunyom is able to help you in any challenges, HIV AIDS, HEPATITIS B, COLD SORES, CANCER, DIABETES, HEART DISEASE, BRAIN TUMOR, ACUTE BRONCHITIS And so many more. For more details Call or what app: +2349060579973 or Email: drohunyom@gmail.com.and  He also have herbs medicine to cured the following diseases; eczema,urethra wart,chronic problems.Herpes, Cancer, Als,Hepatitis, Diabetes, HPV,Infections,ulcer  ETC

    ReplyDelete
  7. So surprise when i found that HSV 1&2 could be cured with Dr Ohunyom herbal remedy, this disease almost destroy my face, and my mouth with sores. i took many traditional medicine here in United state, but none could work. even visited my mother village in South africa still couldn't find a cure, but i was so surprise that after contacting Dr Ohunyom. And after done discussing with him i was cured with his herbal in 2 weeks. i confirmed his good work by my test result, do not delay to contact this true healer. Dr Ohunyom is able to help you in any challenges, HIV AIDS, HEPATITIS B, COLD SORES, CANCER, DIABETES, HEART DISEASE, BRAIN TUMOR, ACUTE BRONCHITIS And so many more. For more details Call or what app: +2349060579973 or Email: drohunyom@gmail.com.and  He also have herbs medicine to cured the following diseases; eczema,urethra wart,chronic problems.Herpes, Cancer, Als,Hepatitis, Diabetes, HPV,Infections,ulcer  ETC

    ReplyDelete
  8. I found out, that taking herbal treatment is the best to get rid of hpv as soon as i feel the symptoms of hpv is appearing, i took the healing process by contacting Dr onokun for natural treatment it works wonders, amazingly ever since I had the herbal treatment i have not feel these horrible disease anymore and my doc told me the virus is gone, i am glad i finally got cured out from this horrible disease. every hpv or herpes patients should also get in touch with this herbalist Dr to get ride of these disease forever his email address; dronokunherbalcure@gmail.com 

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  9. God has sent Dr Onokun to help people out from this horrible virus. i was diagnosis with hpv for 3 years, few months ago a friend introduced me to dr onokun and i only took his natural treatment for a week & 3 days, and i totally got cured with his herbal treatment. if you are suffering from hpv, you don't have to be roaming round dr onokun email is been attached to contact him on email:  dronokunherbalcure@gmail.com

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  10. FINALLY FREE FROM HERPES VIRUSI thought my life had nothing to offer anymore because lifebecame meaningless to me because I had Herpes virus, thesymptoms became very severe and bold and made my familyrun from and abandoned me so they won't get infected. I gaveup everything, my hope, dreams,vision and job because thedoctor told me there's no cure. I consumed so many drugs butthey never cured me but hid the symptoms inside me makingit worse. I was doing some research online someday when Icame across testimonies of some people of how DR Ebhotacured them from Herpes, I never believed at first and thoughtit was a joke but later decided to contact him on the detailsprovided and when I messaged him we talked and he sent mehis herbal medicine and told me to go for a test after twoweeks. Within 7 days of medication the symptomsdisappeared and when I went for a test Lo and behold I wasNEGATIVE by the Doctor Who tested me earlier. Thank you DREbhota because I forever owe you my life and I'll keep ontelling the world about you. If you are going through samesituation worry no more and contact DR Ebhota viadrebhotasolution@gmail. com or WhatsApp him via +2348089535482.he also special on cureing 1. HIV/AIDS2. HERPES 3. CANCER 4.ALS 5. HEPATITIS B 6.DIABETES 7. HUMAN PAPILOMA VIRUS DISEASE(HPV)8. ALZHEIMER 9. LUPUS (Lupus Vulgaris or LupusErythematosu

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