Sunday, January 27, 2019

From Human to Chimp....



Two years ago, researchers from the University of Wisconsin, Madison discovered that the virus which caused the common cold in humans was responsible for the deaths of wild chimpanzees in Uganda. Now, researchers have discovered two more human respiratory viruses among chimps in the same forest.

Between December 2016 and February 2017, the two viral outbreaks occurred within the same community of chimpanzees, creating suspicion that they were caused by the same pathogen. Although the presentation was the same and consistent with viral infection of the respiratory tract, only one of the outbreaks was fatal. The virus responsible for the lethal outbreak was metapneumovirus (MPV), while the other group of chimps that were sick but did not suffer any deaths was infected with parainfluenza 3.

In humans, MPV is rarely lethal, showing that its effects were much stronger in chimps, and though parainfluenza 3 did not cause any deaths, its mortality rate was much higher amongst the chimps relative to humans. The high virulence of parainfluenza 3 and the fact that it spread rapidly to nearly all the chimps suggested that the chimps had no immunity against it and this may have been the first time that humans transferred the virus across species. In fact, the viral genome of parainfluenza 3 found in infected chimps nearly mirrors that of the one found in humans.

While it is unclear how the virus was transferred from human to chimp, the severity of the outbreak has prompted government and conservation groups across the African continent to implement practices such as the use of masks, quarantining before forest entry and the use of hand sanitizers. As research Tony Goldberg summarizes, "All it takes is one person unwittingly carrying a 'common cold' virus to spark a deadly outbreak in apes."

-Riasoya Jodah

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